Browsing by Author "Harris, Marianne"
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Item A Randomized, Open-Label Study of a Nucleoside Analogue Reverse Transcriptase Inhibitor-Sparing Regimen in Antiretroviral-Naive HIV-Infected Patients(2009-03) Harris, Marianne; Côté, Hélène; Ochoa, Claudia; Allavena, Clotilde; Negredo, Eugenia; Thorne, Anona; Cahn, Pedro; Raffi, Francois; Clotet, Bonaventura; Singer, Joel; Montaner, Julio; The CTN 177 Study TeamItem Venous and Arterial Blood Lactate in HIV-Infected Patients(2002-12) Zala, Carlos; Harris, Marianne; Ochoa, Claudia; Tocci, Mariel; Quercia, Romina; Mittelman, Graciela; Graciela, Héctor; Cahn, Pedro; Montaner, Julio SGHyperlactataemia is increasingly recognised as a complication of nucleoside analogue-based antiretroviral therapy [1–5]. There is, however, some debate about the accuracy of peripheral venous blood lactate levels and whether these adequately reflect arterial lactate levels. This correlation has been demonstrated in the non-HIV, emergency medicine literature [6,7], but has not been studied in HIV patients receiving antiretroviral therapy. Therefore, we undertook the present study to compare venous versus arterial lactate levels in HIV patients who had consistently high random venous lactate while receiving chronic stavudine-based antiretroviral therapy.